indazole carboxamide - An Overview
Substitution at R3 using a halogen or alkoxy group (74f–74i) resulted in a slight increase in mobile potency While using the halide analogs (74g–h) exhibiting optimum the potency while in the group. Even more optimization resulted in the invention of 74i–j, with 74k as quite possibly the most Energetic compound inside the series (pIC50 = six.